Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9812973 | 1.00 | MAPT (0.38) | MAPTCACNA1BAPBA1L3MBTL1APP | |
| SCHEMBL3988829 | 0.84 | L3MBTL1 (0.45) | MAPTL3MBTL1CA2 | |
| SCHEMBL9914107 | 0.84 | L3MBTL1 (0.45) | MAPTL3MBTL1CA2 | |
| SCHEMBL4426142 | 0.84 | L3MBTL1 (0.45) | MAPTL3MBTL1CA2 | |
| SCHEMBL3988831 | 0.84 | L3MBTL1 (0.45) | MAPTL3MBTL1CA2 | |
| SCHEMBL1243883 | 0.84 | L3MBTL1 (0.45) | MAPTL3MBTL1CA2 | |
| SCHEMBL3988833 | 0.84 | L3MBTL1 (0.45) | MAPTL3MBTL1CA2 | |
| SCHEMBL4422593 | 0.84 | L3MBTL1 (0.45) | MAPTL3MBTL1CA2 | |
| SCHEMBL4425298 | 0.84 | L3MBTL1 (0.45) | MAPTL3MBTL1CA2 | |
| SCHEMBL12150587 | 0.84 | L3MBTL1 (0.45) | MAPTL3MBTL1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427773-A1 | METHOD OF PREPARATION OF 2',3'-DIDEOXYNUCLEOSIDES | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1991-05-22 | — | — | EP | disclosed |
| US-4987224-A | Method of preparation of 2',3'-dideoxynucleosides | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1991-01-22 | — | — | US | disclosed |
| WO-1990001492-A1 | METHOD OF PREPARATION OF 2',3'-DIDEOXYNUCLEOSIDES | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1990-02-22 | — | — | WO | disclosed |