Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | GBA1 | P04062 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28649464 | 0.89 | ALDH1A1 (0.68) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL5883674 | 0.83 | ALDH1A1 (0.63) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL14621509 | 0.82 | ALDH1A1 (0.60) | ALDH1A1LMNANPSR1CA2GBA1 | |
| SCHEMBL8349568 | 0.82 | ALDH1A1 (0.79) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL757988 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL24370532 | 0.80 | ALDH1A1 (0.63) | ALDH1A1LMNASMN1; SMN2HTR7 | |
| SCHEMBL11196755 | 0.80 | EPHX2 (0.64) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL11512411 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| Formaldehyde SCHEMBL4557832 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL8388144 | 0.79 | ALDH1A1 (0.68) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223593-B1 | PHENOXYALKYLCARBOXYLIC ACIDS AND ESTERS AND THEIR PREPARATION AND PHARMACEUTICAL FORMULATION | GLAXO GROUP LIMITED (GB) | 1991-08-07 | — | — | EP | disclosed |
| EP-0223593-A2 | Phenoxyalkylcarboxylic acids and esters and their preparation and pharmaceutical formulation | GLAXO GROUP LIMITED (GB) | 1987-05-27 | — | — | EP | disclosed |