Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 7/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9550781 | 0.79 | THRB (0.35) | ALOX15ALOX12THRBHSD17B10CYP1A2 | |
| SCHEMBL9550786 | 0.78 | HSD17B10 (0.36) | ALOX15ALOX12THRBHSD17B10CYP1A2 | |
| SCHEMBL9550811 | 0.75 | CA2 (0.41) | ALOX15ALOX12THRBHSD17B10CYP1A2 | |
| SCHEMBL9551111 | 0.74 | HSD17B10 (0.33) | ALOX15ALOX12THRBHSD17B10CYP1A2 | |
| SCHEMBL9550725 | 0.72 | THRB (0.44) | THRBESR1TTRALDH1A1 | |
| SCHEMBL9550713 | 0.71 | THRB (0.37) | ALOX15ALOX12THRBHSD17B10CYP1A2 | |
| SCHEMBL9550802 | 0.70 | HSD17B10 (0.32) | ALOX15ALOX12HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL9550724 | 0.69 | THRB (0.41) | THRBHSD17B10SMN1; SMN2ESR1TTR | |
| SCHEMBL9550717 | 0.68 | THRB (0.40) | ALOX15ALOX12THRBHSD17B10CYP1A2 | |
| SCHEMBL9550790 | 0.68 | ESR1 (0.33) | ALOX15ALOX12THRBHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047593-A | Antiinflammatory And Antiallergy Agents | G. D. SEARLE & CO. (US) | 1991-09-10 | — | — | US | disclosed |