Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813458 | 0.88 | KDM4E (0.52) | MTNR1AMTNR1BMAPTALDH1A1LMNA | |
| SCHEMBL9813466 | 0.86 | MAPT (0.61) | CYP4F2CYP4A11MAPTALDH1A1KDM4E | |
| SCHEMBL15522689 | 0.85 | CYP4F2 (0.64) | CYP4F2CYP4A11ALDH1A1HTTF2RL1 | |
| SCHEMBL9813805 | 0.84 | ALDH1A1 (0.51) | MTNR1AMTNR1BMAPTALDH1A1LMNA | |
| SCHEMBL10581485 | 0.83 | KMT2A (0.48) | MTNR1AMTNR1BALDH1A1LMNAKDM4E | |
| Acetic Acid SCHEMBL10581481 | 0.81 | ALDH1A1 (0.54) | MTNR1AMTNR1BMAPTALDH1A1LMNA | |
| Acetic Acid Methyl Ester SCHEMBL10581477 | 0.81 | ALDH1A1 (0.57) | MTNR1AMTNR1BMAPTALDH1A1LMNA | |
| SCHEMBL313139 | 0.81 | HTT (0.69) | CYP4F2CYP4A11ALDH1A1KDM4EHTT | |
| SCHEMBL5824030 | 0.80 | MAPT (0.46) | CYP4F2CYP4A11MTNR1AMTNR1BMAPT | |
| SCHEMBL12470557 | 0.80 | ALDH1A1 (0.62) | MTNR1AMTNR1BMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297768-B1 | ARYLTHIOALKYLPHENYL CARBOXYLIC ACIDS, COMPOSITIONS CONTAINING SAME AND METHOD OF USE | E.R. Squibb & Sons, Inc. (US) | 1991-07-24 | — | — | EP | claimed |
| EP-0297768-A1 | Arylthioalkylphenyl carboxylic acids, compositions containing same and method of use | E.R. Squibb & Sons, Inc. (US) | 1989-01-04 | — | — | EP | claimed |
| US-4752616-A | Arylthioalkylphenyl carboxylic acids, compositions containing same and method of use | E. R. SQUIBB & SONS, INC. (US) | 1988-06-21 | — | — | US | claimed |
| EP-0297768-B1 | ARYLTHIOALKYLPHENYL CARBOXYLIC ACIDS, COMPOSITIONS CONTAINING SAME AND METHOD OF USE | E.R. Squibb & Sons, Inc. (US) | 1991-07-24 | — | — | EP | disclosed |
| US-4752616-A | Arylthioalkylphenyl carboxylic acids, compositions containing same and method of use | E. R. SQUIBB & SONS, INC. (US) | 1988-06-21 | — | — | US | disclosed |