Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813805 | 0.96 | ALDH1A1 (0.51) | KDM4EPOLBALDH1A1HPGDHSD17B10 | |
| SCHEMBL9813437 | 0.88 | CYP4F2 (0.51) | KDM4EALDH1A1LMNAMTNR1AMTNR1B | |
| Acetic Acid SCHEMBL10581481 | 0.85 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDLMNAMTNR1A | |
| Acetic Acid Methyl Ester SCHEMBL10581477 | 0.82 | ALDH1A1 (0.57) | KDM4EALDH1A1LMNAMTNR1AMTNR1B | |
| SCHEMBL9813446 | 0.81 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL10581485 | 0.81 | KMT2A (0.48) | KDM4EALDH1A1LMNAMTNR1AMTNR1B | |
| SCHEMBL6932432 | 0.81 | KDM4E (0.62) | KDM4EPOLBALDH1A1HPGDPTGS1 | |
| SCHEMBL240822 | 0.80 | KDM4E (0.74) | KDM4EPOLBALDH1A1HSD17B10PTGS1 | |
| SCHEMBL3130467 | 0.79 | ALDH1A1 (0.64) | ALDH1A1LMNAMTNR1AMTNR1BFFAR1 | |
| Hydrochloric Acid SCHEMBL2022863 | 0.78 | KDM4E (0.72) | KDM4EPOLBALDH1A1HSD17B10PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297768-B1 | ARYLTHIOALKYLPHENYL CARBOXYLIC ACIDS, COMPOSITIONS CONTAINING SAME AND METHOD OF USE | E.R. Squibb & Sons, Inc. (US) | 1991-07-24 | — | — | EP | claimed |