Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10578543 | 0.84 | HDAC1 (0.53) | ALDH1A1HDAC1HDAC8LMNAHTT | |
| SCHEMBL9813465 | 0.84 | ALDH1A1 (0.48) | ALDH1A1HDAC1HDAC8LMNAHTT | |
| SCHEMBL9813753 | 0.82 | HDAC1 (0.64) | ALDH1A1HPGDHSD17B10HDAC1HDAC8 | |
| SCHEMBL3250400 | 0.81 | TBXA2R (0.62) | ALDH1A1HPGDHSD17B10HDAC1HDAC8 | |
| SCHEMBL9813436 | 0.81 | HTT (0.62) | ALDH1A1HPGDHSD17B10HTTCA1 | |
| SCHEMBL10578550 | 0.80 | MAPT (0.48) | ALDH1A1EPHX2HDAC1HDAC8LMNA | |
| SCHEMBL10581711 | 0.80 | ALDH1A1 (0.57) | ALDH1A1HPGDHSD17B10HDAC1HDAC8 | |
| SCHEMBL840854 | 0.80 | NR1H4 (0.70) | NR1H4ALDH1A1HPGDHSD17B10EPHX2 | |
| SCHEMBL23193744 | 0.79 | ALDH1A1 (0.64) | ALDH1A1HPGDHSD17B10HTTCA2 | |
| Methane SCHEMBL17237476 | 0.78 | NR1H4 (0.68) | NR1H4ALDH1A1EPHX2SLC13A5RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297768-B1 | ARYLTHIOALKYLPHENYL CARBOXYLIC ACIDS, COMPOSITIONS CONTAINING SAME AND METHOD OF USE | E.R. Squibb & Sons, Inc. (US) | 1991-07-24 | — | — | EP | claimed |
| EP-0297768-A1 | Arylthioalkylphenyl carboxylic acids, compositions containing same and method of use | E.R. Squibb & Sons, Inc. (US) | 1989-01-04 | — | — | EP | claimed |
| US-4752616-A | Arylthioalkylphenyl carboxylic acids, compositions containing same and method of use | E. R. SQUIBB & SONS, INC. (US) | 1988-06-21 | — | — | US | claimed |
| EP-0297768-B1 | ARYLTHIOALKYLPHENYL CARBOXYLIC ACIDS, COMPOSITIONS CONTAINING SAME AND METHOD OF USE | E.R. Squibb & Sons, Inc. (US) | 1991-07-24 | — | — | EP | disclosed |
| EP-0297768-A1 | Arylthioalkylphenyl carboxylic acids, compositions containing same and method of use | E.R. Squibb & Sons, Inc. (US) | 1989-01-04 | — | — | EP | disclosed |
| US-4752616-A | Arylthioalkylphenyl carboxylic acids, compositions containing same and method of use | E. R. SQUIBB & SONS, INC. (US) | 1988-06-21 | — | — | US | disclosed |