Methane

Methane

SCHEMBL17237476

C.CC(C)(C)c1ccc(CC(=O)O)cc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 9/20 0.68
EPHX2 P34913 1/20 0.68
RXRA P19793 1/20 0.66
RXRB P28702 1/20 0.66
RXRG P48443 1/20 0.66
CA2 P00918 1/20 0.54
CAMK2A Q9UQM7 1/20 0.54
AKR1B1 P15121 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
SLC13A5 Q86YT5 2/20 0.51
ABCC4 O15439 1/20 0.50
LMNA P02545 1/20 0.50
GAA P10253 1/20 0.50
TSHR P16473 1/20 0.50
PTGS1 P23219 1/20 0.50
HTT P42858 1/20 0.50
MAPT P10636 1/20 0.50
ALDH1A1 P00352 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL840854 0.98 NR1H4 (0.70) NR1H4EPHX2RXRARXRBRXRG
Hydrochloric Acid SCHEMBL2528372 0.96 NR1H4 (0.68) NR1H4EPHX2RXRARXRBRXRG
SCHEMBL13008812 0.92 RXRA (0.77) NR1H4EPHX2RXRARXRBRXRG
SCHEMBL27940962 0.85 RXRA (0.58) NR1H4EPHX2RXRARXRBRXRG
SCHEMBL1061936 0.83 RXRA (0.56) NR1H4EPHX2RXRARXRBRXRG
SCHEMBL29129862 0.83 NR1H4 (0.67) NR1H4EPHX2RXRARXRBRXRG
SCHEMBL9525909 0.83 NR1H4 (0.53) NR1H4EPHX2RXRARXRBRXRG
SCHEMBL7300696 0.82 NR1H4 (1.00) NR1H4EPHX2SMN1; SMN2LMNAMAPT
SCHEMBL9785033 0.82 RXRA (0.54) NR1H4EPHX2RXRARXRBRXRG
SCHEMBL21133929 0.82 RXRA (0.54) NR1H4EPHX2RXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2037866-B1 FLAVORS FOR ORAL COMPOSITIONS PROCTER & GAMBLE (US) 2015-11-11 EP claimed
CN-114269365-A Thermally gelled cannabinoid compositions and methods of making and using same 埃克索运营公司 2022-04-01 CN disclosed
CN-101677933-B Alkoxylated mono-, di-, and polyol phosphate esters in oral care formulations and methods of use thereof RHODIA 2013-07-17 CN disclosed
CN-101677933-A Alkoxylated mono-, di-, and polyol phosphate esters in oral care formulations and methods of use thereof RHODIA 2010-03-24 CN disclosed