Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813444 | 0.92 | MEN1 (0.36) | — | |
| SCHEMBL9813450 | 0.83 | CYP4F2 (0.38) | — | |
| SCHEMBL10633026 | 0.81 | — | — | |
| SCHEMBL5872189 | 0.78 | MEN1 (0.39) | — | |
| SCHEMBL9701765 | 0.71 | TRPA1 (0.30) | — | |
| SCHEMBL5871216 | 0.69 | PPARA (0.40) | — | |
| SCHEMBL5871994 | 0.68 | MME (0.37) | SIGMAR1 | |
| SCHEMBL9671990 | 0.65 | TDP1 (0.48) | SIGMAR1 | |
| SCHEMBL9185293 | 0.64 | TRPA1 (0.40) | SIGMAR1 | |
| SCHEMBL1627502 | 0.64 | PPARA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297768-B1 | ARYLTHIOALKYLPHENYL CARBOXYLIC ACIDS, COMPOSITIONS CONTAINING SAME AND METHOD OF USE | E.R. Squibb & Sons, Inc. (US) | 1991-07-24 | — | — | EP | disclosed |
| EP-0297768-A1 | Arylthioalkylphenyl carboxylic acids, compositions containing same and method of use | E.R. Squibb & Sons, Inc. (US) | 1989-01-04 | — | — | EP | disclosed |