Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602863 | 0.82 | CYP3A4 (0.40) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL9701765 | 0.82 | TRPA1 (0.30) | TRPA1 | |
| SCHEMBL5871994 | 0.82 | MME (0.37) | TAAR1SIGMAR1EPHX1 | |
| SCHEMBL6160186 | 0.80 | TAAR1 (0.41) | TAAR1SIGMAR1CYP2D6 | |
| SCHEMBL5871216 | 0.80 | PPARA (0.40) | TRPA1 | |
| SCHEMBL9602332 | 0.80 | PDE4A (0.35) | — | |
| SCHEMBL5872189 | 0.80 | MEN1 (0.39) | — | |
| SCHEMBL8807198 | 0.78 | ALDH1A1 (0.36) | CYP2A6 | |
| SCHEMBL7969044 | 0.78 | POLB (0.37) | TRPA1SLC6A2SLC6A4SLC6A3POLB | |
| SCHEMBL7981785 | 0.78 | ATM (0.43) | MAOACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422329-B1 | Substituted dibenzofurans and methods of using same | EURO CELTIQUE SA (LU) | 1995-07-26 | — | — | EP | disclosed |
| EP-0422329-A1 | Substituted dibenzofurans and methods of using same | Euro-Celtique S.A. (LU) | 1991-04-17 | — | — | EP | disclosed |