Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.33 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835731 | 0.86 | ALDH1A1 (0.37) | ALDH1A1SLC18A3CHRM5CHRM1CHRM3 | |
| SCHEMBL16371608 | 0.83 | TSHR (0.43) | ALDH1A1SLC18A3CHRM5CHRM1CHRM3 | |
| Cyclohexane SCHEMBL9813712 | 0.82 | CHRM2 (0.33) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL10682961 | 0.81 | ALDH1A1 (0.33) | ALDH1A1SLC18A3CHRM5CHRM1CHRM3 | |
| SCHEMBL11526038 | 0.80 | SLC18A3 (0.35) | ALDH1A1SLC18A3 | |
| SCHEMBL11811701 | 0.79 | ALDH1A1 (0.39) | ALDH1A1SLC18A3CHRM5CHRM1CHRM3 | |
| SCHEMBL11177357 | 0.77 | TSHR (0.36) | ALDH1A1SLC18A3CHRM5CHRM1CHRM3 | |
| SCHEMBL11173444 | 0.77 | KMT2A (0.41) | ALDH1A1SLC18A3SMN1; SMN2TSHRGAA | |
| SCHEMBL11741459 | 0.77 | ALDH1A1 (0.38) | ALDH1A1SLC18A3CHRM5CHRM1CHRM3 | |
| SCHEMBL14947111 | 0.76 | MEN1 (0.33) | ALDH1A1SLC18A3CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0163245-B1 | DERIVATIVES OF ALKYL-SUBSTITUTED 4-HYDROXY-METHYL-PIPERIDINE AND USE THEREOF AS STABILIZERS | AUSIMONT S.r.l. (IT) | 1991-07-31 | — | — | EP | disclosed |
| EP-0163245-A2 | Derivatives of alkyl-substituted 4-hydroxy-methyl-piperidine and use thereof as stabilizers | AUSIMONT S.r.l. (IT) | 1985-12-04 | — | — | EP | disclosed |