Cyclohexane

Cyclohexane

SCHEMBL9813712

C1CCCCC1.CC1CC(C)(C)N(CCOC(N)=O)C(C)(C)C1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.33
CHRM4 P08173 2/20 0.33
CHRM5 P08912 2/20 0.33
CHRM1 P11229 2/20 0.33
CHRM3 P20309 2/20 0.33
ALOX15 P16050 2/20 0.33
CHRNB2 P17787 2/20 0.33
CHRNA4 P43681 2/20 0.33
LMNA P02545 1/20 0.33
HTR1A P08908 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
CHRNA7 P36544 1/20 0.33
CTNNB1 P35222 1/20 0.33
CYP2D6 P10635 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
CHRNB4 P30926 1/20 0.30
CHRNA3 P32297 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9813719 0.82 ALDH1A1 (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL9813614 0.78 CHRM2 (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3
Methyl Carbamate SCHEMBL9813718 0.74 EPHX2 (0.35) CYP2C19
Methyl Carbamate SCHEMBL9813625 0.72 PAOX (0.30)
SCHEMBL1702771 0.70 TSHR (0.34) CHRM2CHRM4CHRM5CHRM1CHRM3
Stearic Acid SCHEMBL9813677 0.69 DGKA (0.48) ALOX15TSHRMEN1KMT2A
SCHEMBL9835731 0.69 ALDH1A1 (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL11171564 0.69 ATM (0.37) TSHRKMT2A
SCHEMBL13121619 0.68 TSHR (0.33) TSHR
SCHEMBL10045651 0.67 GAA (0.40) CYP2C19CYP2D6KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0163245-B1 DERIVATIVES OF ALKYL-SUBSTITUTED 4-HYDROXY-METHYL-PIPERIDINE AND USE THEREOF AS STABILIZERS AUSIMONT S.r.l. (IT) 1991-07-31 EP disclosed
US-4772708-A STABILIZERS FOR POLYMERS AUSIMONT S.P.A. (IT) 1988-09-20 US disclosed
EP-0163245-A2 Derivatives of alkyl-substituted 4-hydroxy-methyl-piperidine and use thereof as stabilizers AUSIMONT S.r.l. (IT) 1985-12-04 EP disclosed