Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.47 |
| ▸ | F10 | P00742 | 4/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.47 |
| ▸ | F7 | P08709 | 4/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | F3 | P13726 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | ACACB | O00763 | 3/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10784225 | 1.00 | F2 (0.47) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL10600559 | 1.00 | F2 (0.47) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL7271123 | 0.88 | F2 (0.48) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL10346671 | 0.87 | NPSR1 (0.53) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL10783267 | 0.87 | NPSR1 (0.53) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL10005610 | 0.87 | CTSL (0.46) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL2116716 | 0.87 | CTSL (0.46) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL7311447 | 0.87 | CTSL (0.46) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL10778740 | 0.87 | F2 (0.44) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL10039872 | 0.87 | CTSL (0.46) | F2F10PRSS1F7PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0201039-B1 | L-AMINOACYLASES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-07-31 | — | — | EP | disclosed |
| EP-0174375-B1 | PROCESS FOR PREPARING N-ACYLPHENYLALANINES | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-05-02 | — | — | EP | disclosed |
| EP-0141613-B1 | A PROCESS FOR PRODUCING AN OPTICALLY ACTIVE 3-(3,4-DIHYDROXPHENYL) SERINE AND A PROTECED DERIVATIVE THEREOF | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1989-02-01 | — | — | EP | disclosed |
| US-4745067-A | HYDROLYTIC ENZYME WHICH ACTS ON N-ACYL-GROUPS | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1988-05-17 | — | — | US | disclosed |
| US-4699879-A | ENZYMIC DEACYLATION | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1987-10-13 | — | — | US | disclosed |
| US-4675439-A | CATALYTIC REDUCTION OF N-ACYL-B-PHENYLSERINE | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1987-06-23 | — | — | US | disclosed |
| EP-0201039-A2 | L-aminoacylases | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1986-11-12 | — | — | EP | disclosed |
| EP-0174375-A1 | PROCESS FOR PREPARING N-ACYLPHENYLALANINES | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1986-03-19 | — | — | EP | disclosed |
| EP-0141613-A2 | A process for producing an optically active 3-(3,4-dihydroxphenyl) serine and a proteced derivative thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1985-05-15 | — | — | EP | disclosed |