Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813785 | 0.96 | HPGD (0.49) | ALDH1A1HPGDHSD17B10FFAR1AKR1B1 | |
| SCHEMBL9813758 | 0.85 | ALDH1A1 (0.48) | ALDH1A1HPGDHSD17B10FFAR1AKR1B1 | |
| SCHEMBL10583226 | 0.82 | ALDH1A1 (0.53) | ALDH1A1HPGDHSD17B10FFAR1AKR1B1 | |
| SCHEMBL10582712 | 0.81 | ALDH1A1 (0.46) | ALDH1A1HPGDHSD17B10FFAR1AKR1B1 | |
| SCHEMBL10582502 | 0.78 | ALDH1A1 (0.53) | ALDH1A1HPGDHSD17B10FFAR1AKR1B1 | |
| SCHEMBL10582820 | 0.77 | ALDH1A1 (0.51) | ALDH1A1HPGDHSD17B10FFAR1AKR1B1 | |
| SCHEMBL9813776 | 0.77 | ALDH1A1 (0.48) | ALDH1A1HPGDHSD17B10FFAR1AKR1B1 | |
| SCHEMBL7063606 | 0.75 | MCHR1 (0.36) | ALDH1A1HPGDHSD17B10LMNATDP1 | |
| SCHEMBL4970664 | 0.74 | AKR1B1 (0.74) | ALDH1A1HPGDHSD17B10FFAR1AKR1B1 | |
| SCHEMBL10579631 | 0.73 | ALDH1A1 (0.49) | ALDH1A1HPGDHSD17B10FFAR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301421-B1 | SULFUR COMPOUNDS, PROCESS FOR THEIR PREPARATION AND MEDICINES | Roche Diagnostics GmbH (DE) | 1991-08-28 | — | — | EP | claimed |
| EP-0301421-B1 | SULFUR COMPOUNDS, PROCESS FOR THEIR PREPARATION AND MEDICINES | Roche Diagnostics GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |
| EP-0301421-A2 | Sulfur compounds, process for their preparation and medicines | Roche Diagnostics GmbH (DE) | 1989-02-01 | — | — | EP | disclosed |