Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 13/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813783 | 0.93 | PTGDR2 (0.51) | PTGDR2L3MBTL1MAPTHSD11B1GAA | |
| SCHEMBL9813830 | 0.91 | PTGDR2 (0.47) | PTGDR2L3MBTL1MAPTHSD11B1GAA | |
| SCHEMBL24079456 | 0.87 | PTGDR2 (0.52) | PTGDR2L3MBTL1MAPTPTGDR | |
| SCHEMBL9836406 | 0.81 | TBXA2R (0.55) | PTGDR2MAPTGAA | |
| SCHEMBL10580468 | 0.81 | HSD11B1 (0.52) | HSD11B1GAAHTTAKR1B1MMP3 | |
| SCHEMBL13106960 | 0.75 | L3MBTL1 (0.46) | PTGDR2L3MBTL1MAPT | |
| SCHEMBL9074110 | 0.73 | HSD11B1 (0.50) | HSD11B1GAAHTTMMP3 | |
| SCHEMBL9768486 | 0.73 | PTGIR (0.55) | GAAHTT | |
| SCHEMBL4752622 | 0.73 | L3MBTL1 (0.63) | PTGDR2L3MBTL1MAPT | |
| SCHEMBL7340039 | 0.73 | L3MBTL1 (0.63) | PTGDR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301421-B1 | SULFUR COMPOUNDS, PROCESS FOR THEIR PREPARATION AND MEDICINES | Roche Diagnostics GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |
| EP-0301421-A2 | Sulfur compounds, process for their preparation and medicines | Roche Diagnostics GmbH (DE) | 1989-02-01 | — | — | EP | disclosed |