Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813796 | 0.96 | ALDH1A1 (0.56) | ALDH1A1HPGDHSD17B10KMT2AGAA | |
| SCHEMBL9813781 | 0.83 | ALDH1A1 (0.50) | ALDH1A1HPGDHSD17B10KMT2AGAA | |
| SCHEMBL9813753 | 0.82 | HDAC1 (0.64) | ALDH1A1HPGDHSD17B10GAAHDAC1 | |
| SCHEMBL9659233 | 0.80 | ALDH1A1 (0.64) | ALDH1A1GAAPOLBTBXA2RCA12 | |
| SCHEMBL9813869 | 0.80 | ALDH1A1 (0.51) | ALDH1A1HPGDHSD17B10KMT2AGAA | |
| SCHEMBL3250400 | 0.78 | TBXA2R (0.62) | ALDH1A1HPGDHSD17B10KMT2AGAA | |
| SCHEMBL10581074 | 0.78 | HDAC1 (0.58) | ALDH1A1HPGDHSD17B10GAAHDAC1 | |
| SCHEMBL9813824 | 0.77 | HDAC1 (0.48) | ALDH1A1HPGDHSD17B10GAAHDAC1 | |
| SCHEMBL10584188 | 0.74 | TBXA2R (0.60) | ALDH1A1HPGDHSD17B10KMT2AGAA | |
| SCHEMBL10587732 | 0.74 | HDAC1 (0.54) | ALDH1A1HPGDHSD17B10GAAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301421-B1 | SULFUR COMPOUNDS, PROCESS FOR THEIR PREPARATION AND MEDICINES | Roche Diagnostics GmbH (DE) | 1991-08-28 | — | — | EP | claimed |
| EP-0301421-B1 | SULFUR COMPOUNDS, PROCESS FOR THEIR PREPARATION AND MEDICINES | Roche Diagnostics GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |
| EP-0301421-A2 | Sulfur compounds, process for their preparation and medicines | Roche Diagnostics GmbH (DE) | 1989-02-01 | — | — | EP | disclosed |