Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4241160 | 0.80 | DRD3 (0.60) | KMT2AMEN1LMNAGAARAD52 | |
| SCHEMBL10963450 | 0.80 | KMT2A (0.44) | KMT2AMEN1LMNAGAARAD52 | |
| SCHEMBL14585956 | 0.79 | ALDH1A1 (0.48) | KMT2AMEN1LMNAGAARAD52 | |
| SCHEMBL16518624 | 0.76 | ALDH1A1 (0.59) | KMT2AMEN1LMNAGAARAD52 | |
| Amifloxacin SCHEMBL48001 | 0.75 | ALDH1A1 (0.70) | KMT2AMEN1LMNAGAARAD52 | |
| Amifloxacin SCHEMBL28198749 | 0.75 | ALDH1A1 (0.70) | KMT2AMEN1LMNAGAARAD52 | |
| Amifloxacin SCHEMBL29371634 | 0.75 | ALDH1A1 (0.70) | KMT2AMEN1LMNAGAARAD52 | |
| Amifloxacin SCHEMBL9788088 | 0.75 | ALDH1A1 (0.69) | KMT2AMEN1LMNAGAARAD52 | |
| SCHEMBL10921339 | 0.73 | ALDH1A1 (0.55) | KMT2AMEN1LMNAGAARAD52 | |
| Amifloxacin SCHEMBL193463 | 0.72 | KDM4E (0.74) | KMT2AMEN1LMNAGAARAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0169105-B1 | CONTROLLED POROSITY OSMOTIC PUMP | MERCK & CO. INC. (US) | 1991-08-07 | — | — | EP | disclosed |