Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4241160 | 0.80 | DRD3 (0.60) | KMT2AMEN1LMNAALDH1A1DRD3 | |
| SCHEMBL9814052 | 0.80 | KMT2A (0.44) | KMT2AMEN1LMNAALDH1A1DRD3 | |
| SCHEMBL14585956 | 0.79 | ALDH1A1 (0.48) | KMT2AMEN1LMNAALDH1A1DRD3 | |
| SCHEMBL10925789 | 0.75 | ALDH1A1 (0.70) | KMT2AMEN1LMNAALDH1A1DRD3 | |
| SCHEMBL10921678 | 0.68 | ALDH1A1 (0.65) | KMT2AMEN1LMNAALDH1A1DRD3 | |
| SCHEMBL10385621 | 0.68 | DRD3 (0.44) | KMT2AMEN1LMNAALDH1A1DRD3 | |
| SCHEMBL6801016 | 0.67 | KMT2A (0.44) | KMT2AMEN1LMNAALDH1A1DRD3 | |
| SCHEMBL29053157 | 0.67 | HSD17B10 (0.53) | KMT2AMEN1LMNAALDH1A1DRD3 | |
| SCHEMBL30570719 | 0.67 | HSD17B10 (0.53) | KMT2AMEN1LMNAALDH1A1DRD3 | |
| SCHEMBL7262142 | 0.67 | HSD17B10 (0.61) | KMT2AMEN1LMNAALDH1A1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090424-B1 | NEW QUINOLONE COMPOUNDS AND PREPARATION THEREOF | STERLING DRUG INC. (US) | 1986-05-28 | — | — | EP | claimed |