Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9814385 | 0.92 | TAS1R3 (0.43) | TAS1R3TAS1R1TSHRCA12CA1 | |
| SCHEMBL9814420 | 0.86 | TAS1R3 (0.42) | TAS1R3TAS1R1TSHRCA12CA1 | |
| SCHEMBL9814426 | 0.85 | TAS1R3 (0.44) | TAS1R3TAS1R1TSHRCA12CA1 | |
| SCHEMBL28471055 | 0.84 | TAS1R3 (0.55) | TAS1R3TAS1R1TSHRCA12CA1 | |
| SCHEMBL9814411 | 0.83 | TAS1R3 (0.43) | TAS1R3TAS1R1TSHRCA12CA1 | |
| SCHEMBL12922588 | 0.81 | TAS1R3 (0.47) | TAS1R3TAS1R1TSHRCA12CA1 | |
| SCHEMBL9814424 | 0.80 | TAS1R3 (0.44) | TAS1R3TAS1R1TSHRCA12CA1 | |
| SCHEMBL821210 | 0.77 | CA12 (0.61) | TAS1R3TAS1R1TSHRCA12CA1 | |
| SCHEMBL29030418 | 0.77 | CA12 (0.47) | TAS1R3TAS1R1TSHRCA12CA1 | |
| SCHEMBL27261839 | 0.77 | ALDH1A1 (0.56) | TSHRALDH1A1L3MBTL1KDM4EPDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0211104-B1 | COMPOSITES | Nippon Shiken Dental Co., Ltd. (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-4705836-A | Polymerization composition containing vinyl benzoic acid or a derivative thereof and a vinyl compound | NIPPON SHIKEN DENTAL CO., LTD. (JP) | 1987-11-10 | — | — | US | disclosed |
| EP-0211104-A2 | Composites | Nippon Shiken Dental Co., Ltd. (JP) | 1987-02-25 | — | — | EP | disclosed |