Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18659704 | 0.89 | AR (0.50) | KDM4EMAPTHPGDPOLBAR | |
| SCHEMBL5987289 | 0.87 | AR (0.62) | KDM4EMAPTHPGDPOLBAR | |
| SCHEMBL2418527 | 0.84 | CACNA1H (0.46) | KDM4EMAPTHPGDPOLBAR | |
| SCHEMBL18659702 | 0.82 | AR (0.50) | KDM4EMAPTHPGDPOLBAR | |
| SCHEMBL15340808 | 0.81 | KDM4E (0.53) | KDM4EMAPTHPGDPOLBAR | |
| SCHEMBL7795894 | 0.81 | CACNA1H (0.44) | KDM4EMAPTHPGDPOLBAR | |
| SCHEMBL5681325 | 0.81 | HTR3E (0.49) | KDM4EMAPTARALDH1A1HTT | |
| SCHEMBL21066380 | 0.81 | EGLN1 (0.44) | ARHTTCACNA1HEGLN1LMNA | |
| SCHEMBL12020706 | 0.81 | MAPT (0.57) | KDM4EMAPTHPGDPOLBAR | |
| SCHEMBL15330111 | 0.78 | KDM4E (0.53) | KDM4EMAPTHPGDPOLBAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251013-B1 | FLUORINE CONTAINING O-AMINOPHENOLS | BAYER AG (DE) | 1991-08-21 | — | — | EP | disclosed |
| EP-0251013-A2 | Fluorine containing o-aminophenols | BAYER AG (DE) | 1988-01-07 | — | — | EP | disclosed |