Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21543853 | 0.85 | TDP1 (0.55) | TDP1KDM4ENPC1RAB9AKMT2A | |
| SCHEMBL7797959 | 0.84 | TDP1 (0.58) | TDP1KDM4ENPC1RAB9AKMT2A | |
| SCHEMBL787525 | 0.83 | KDM4E (0.56) | KDM4ENPC1RAB9AKMT2APOLB | |
| SCHEMBL3207510 | 0.82 | CA12 (0.64) | TDP1KDM4ENPC1RAB9AKMT2A | |
| SCHEMBL16955174 | 0.82 | TDP1 (0.52) | TDP1KDM4ENPC1RAB9AKMT2A | |
| SCHEMBL4125549 | 0.81 | MAOB (0.58) | KDM4ENPC1RAB9AKMT2AMEN1 | |
| SCHEMBL21447016 | 0.81 | TDP1 (0.51) | TDP1KDM4ENPC1RAB9AKMT2A | |
| SCHEMBL16955172 | 0.81 | TDP1 (0.51) | TDP1KDM4ENPC1RAB9AKMT2A | |
| SCHEMBL10362606 | 0.81 | ALDH1A1 (0.58) | TDP1KDM4ENPC1RAB9AKMT2A | |
| SCHEMBL31459933 | 0.81 | KDM4E (0.54) | TDP1KDM4ENPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162723-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-05-29 | — | — | EP | disclosed |
| US-4981509-A | Plant growth regulators | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-01-01 | — | — | US | disclosed |
| US-4877442-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-10-31 | — | — | US | disclosed |
| US-4871847-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-10-03 | — | — | US | disclosed |
| US-4849010-A | Herbicidal sulfonamides | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1989-07-18 | — | — | US | disclosed |
| US-4724039-A | RICE CROP | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-02-09 | — | — | US | disclosed |
| US-4710221-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-12-01 | — | — | US | disclosed |
| EP-0162723-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-11-27 | — | — | EP | disclosed |