SCHEMBL9814730

SCHEMBL9814730

O=C1NS(=O)(=O)c2cc(OCc3ccccc3)ccc21

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 10/20 0.59
MAOA P21397 8/20 0.59
TOP1 P11387 1/20 0.54
GSTP1 P09211 1/20 0.49
CA12 O43570 3/20 0.49
CA9 Q16790 3/20 0.49
CA2 P00918 2/20 0.49
KDM4E B2RXH2 1/20 0.49
USP2 O75604 1/20 0.49
CA1 P00915 1/20 0.49
LMNA P02545 1/20 0.49
BCHE P06276 1/20 0.49
CA4 P22748 1/20 0.49
CA6 P23280 1/20 0.49
CA5A P35218 1/20 0.49
CA7 P43166 1/20 0.49
KMT2A Q03164 1/20 0.49
CA14 Q9ULX7 1/20 0.49
CA5B Q9Y2D0 1/20 0.49
NSD2 O96028 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12745892 0.80 GSTP1 (0.49) MAOBMAOAGSTP1CA12CA9
SCHEMBL11681555 0.80 CA12 (0.53) CA12CA9CA2KDM4EUSP2
SCHEMBL7340305 0.77 CA12 (0.50) MAOBMAOACA12CA9CA2
SCHEMBL7379163 0.75 MAOA (1.00) MAOBMAOATOP1GSTP1NSD2
SCHEMBL20443154 0.74 CA12 (0.57) CA12CA9CA2KDM4EUSP2
SCHEMBL5186168 0.74 CA12 (0.63) CA12CA9CA2KDM4EUSP2
SCHEMBL20423635 0.74 CA12 (0.47) CA12CA9CA2KDM4EUSP2
SCHEMBL20437010 0.74 PTPN11 (0.48) CA12CA9CA2CA1KMT2A
SCHEMBL3164814 0.73 TOP1 (0.58) MAOBMAOATOP1GSTP1CA12
SCHEMBL24701048 0.72 TOP1 (0.71) MAOBMAOATOP1GSTP1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0235449-B1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-09-11 EP disclosed
EP-0162723-B1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-05-29 EP disclosed
US-4981509-A Plant growth regulators E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-01-01 US disclosed
US-4877442-A Herbicidal sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-10-31 US disclosed
US-4871847-A Herbicidal sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-10-03 US disclosed
US-4849010-A Herbicidal sulfonamides E. I. DUPONT DE NEMOURS AND COMPANY (US) 1989-07-18 US disclosed
US-4724039-A RICE CROP E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-02-09 US disclosed
US-4710221-A Herbicidal sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-12-01 US disclosed
EP-0235449-A1 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-09-09 EP disclosed
EP-0162723-A2 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-11-27 EP disclosed