Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 4/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9814803 | 1.00 | SNCA (0.50) | SNCACYP19A1MAPTRAB9ANPC1 | |
| SCHEMBL11299294 | 0.84 | CYP19A1 (0.62) | SNCACYP19A1MAPTRAB9ANPC1 | |
| SCHEMBL10940074 | 0.84 | CYP19A1 (0.62) | SNCACYP19A1MAPTRAB9ANPC1 | |
| SCHEMBL21574808 | 0.83 | NR1H3 (0.44) | APPNFE2L2CYP1B1 | |
| SCHEMBL29392092 | 0.83 | NR1H3 (0.44) | APPNFE2L2CYP1B1 | |
| SCHEMBL553822 | 0.83 | NR1H3 (0.44) | APPNFE2L2CYP1B1 | |
| SCHEMBL553823 | 0.83 | NR1H3 (0.44) | APPNFE2L2CYP1B1 | |
| SCHEMBL9798883 | 0.82 | NFE2L2 (0.56) | SNCACYP19A1MAPTRAB9ANPC1 | |
| SCHEMBL9798893 | 0.82 | NFE2L2 (0.56) | SNCACYP19A1MAPTRAB9ANPC1 | |
| SCHEMBL22624707 | 0.80 | ERN1 (0.54) | SNCAMAPTRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170181997-A1 | ARYL ISONITRILE COMPOUNDS AS A NEW CLASS OF POTENT, BROAD-SPECTRUM ANTIFUNGAL COMPOUNDS | PURDUE RESEARCH FOUNDATION (US) | 2017-06-29 | — | — | US | disclosed |
| EP-0438557-A1 | NON-LINEAR OPTICALLY ACTIVE POLYIMIDES | MERCK PATENT GmbH (DE) | 1991-07-31 | — | — | EP | disclosed |
| WO-1991003001-A1 | NON-LINEAR OPTICALLY ACTIVE POLYIMIDES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170181997-A1 | ARYL ISONITRILE COMPOUNDS AS A NEW CLASS OF POTENT, BROAD-SPECTRUM ANTIFUNGAL COMPOUNDS | AHR, CYP3A4, NAT1 | SNCA 3642/4885CYP19A1 260/4885MAPT 2612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.