Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | TK1 | P04183 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | POLA1 | P09884 | 1/20 | 0.39 |
| ▸ | POLD1 | P28340 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9814873 | 0.97 | ABCG2 (0.40) | ABCG2ABCB1TK1POLBPOLA1 | |
| SCHEMBL9814872 | 0.97 | TK1 (0.41) | ABCG2ABCB1TK1POLBPOLA1 | |
| SCHEMBL9814738 | 0.95 | TK1 (0.41) | ABCG2ABCB1TK1POLBPOLA1 | |
| SCHEMBL9814855 | 0.90 | TK1 (0.41) | ABCG2ABCB1TK1POLBPOLA1 | |
| SCHEMBL9814884 | 0.89 | TK1 (0.42) | ABCG2ABCB1TK1POLBPOLA1 | |
| SCHEMBL9814768 | 0.88 | TK1 (0.42) | ABCG2ABCB1TK1POLBPOLA1 | |
| SCHEMBL9814737 | 0.86 | TK1 (0.41) | ABCG2ABCB1TK1POLBPOLA1 | |
| SCHEMBL9814934 | 0.83 | TK1 (0.43) | TK1POLBPOLA1POLD1 | |
| SCHEMBL15643038 | 0.80 | POLB (0.62) | ABCG2ABCB1TK1POLBPOLA1 | |
| SCHEMBL9011028 | 0.80 | TK1 (0.53) | TK1POLBPOLA1POLD1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445201-A1 | NUCLEOSIDE ANALOGUES | MEDICAL RESEARCH COUNCIL (GB) | 1991-09-11 | — | — | EP | claimed |
| WO-1990005736-A2 | NUCLEOSIDE ANALOGUES | MEDICAL RESEARCH COUNCIL (GB) | 1990-05-31 | — | — | WO | claimed |
| EP-0445201-A1 | NUCLEOSIDE ANALOGUES | MEDICAL RESEARCH COUNCIL (GB) | 1991-09-11 | — | — | EP | disclosed |
| WO-1990005736-A2 | NUCLEOSIDE ANALOGUES | MEDICAL RESEARCH COUNCIL (GB) | 1990-05-31 | — | — | WO | disclosed |