Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | POLA1 | P09884 | 1/20 | 0.48 |
| ▸ | POLD1 | P28340 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2379396 | 0.91 | POLB (0.56) | TK1LMNATSHRPOLBALB | |
| SCHEMBL4596737 | 0.86 | TK1 (0.55) | TK1LMNATSHRPOLBALB | |
| SCHEMBL288450 | 0.85 | TK1 (0.56) | TK1POLB | |
| SCHEMBL9814884 | 0.83 | TK1 (0.42) | TK1LMNATSHRPOLBALB | |
| SCHEMBL9814768 | 0.83 | TK1 (0.42) | TK1LMNATSHRPOLBALB | |
| SCHEMBL25752637 | 0.82 | TK1 (0.60) | TK1POLB | |
| SCHEMBL25756099 | 0.82 | TK1 (0.60) | TK1POLB | |
| SCHEMBL7201324 | 0.82 | TK1 (0.60) | TK1POLB | |
| SCHEMBL25700727 | 0.82 | TK1 (0.60) | TK1POLB | |
| SCHEMBL9814738 | 0.82 | TK1 (0.41) | TK1LMNATSHRPOLBALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585364-A | SIDE EFFECT REDUCTION WHEN ADMINISTERED TO TREAT THE AIDS VIRUS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-12-17 | — | — | US | disclosed |
| EP-0392791-B1 | Antiviral compounds | BRITISH TECH GROUP (GB) | 1995-08-02 | — | — | EP | disclosed |
| WO-1990012023-A1 | ANTIVIRAL COMPOUNDS | WALKER RICHARD THOMAS (GB) | 1990-10-18 | — | — | WO | disclosed |
| EP-0392791-A1 | Antiviral compounds | BTG INTERNATIONAL LIMITED (GB) | 1990-10-17 | — | — | EP | disclosed |