Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 3/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 5/20 | 0.33 |
| ▸ | MMP1 | P03956 | 4/20 | 0.33 |
| ▸ | MMP3 | P08254 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2872488 | 0.81 | BMP1 (0.45) | BMP1FOLH1ENPEPANPEPMMP9 | |
| SCHEMBL2873906 | 0.80 | — | — | |
| SCHEMBL2874729 | 0.78 | BMP1 (0.42) | BMP1FOLH1ENPEPANPEPMMP9 | |
| SCHEMBL6209739 | 0.78 | BMP1 (0.42) | BMP1FOLH1ENPEPANPEPMMP9 | |
| SCHEMBL2868527 | 0.76 | FOLH1 (0.44) | BMP1FOLH1MMP9MMP1MMP3 | |
| SCHEMBL15499529 | 0.72 | BMP1 (0.41) | BMP1FOLH1ENPEPANPEPMMP9 | |
| SCHEMBL14542794 | 0.72 | LMNA (0.43) | BMP1LMNAPOLBMMP9ALDH1A1 | |
| SCHEMBL24729155 | 0.72 | FOLH1 (0.52) | BMP1FOLH1LMNAENPEPANPEP | |
| SCHEMBL2868532 | 0.72 | FOLH1 (0.41) | BMP1FOLH1ENPEPANPEPMMP9 | |
| SCHEMBL22300362 | 0.71 | BMP1 (0.42) | BMP1LMNAENPEPANPEPPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010103-A | Anticarcinogenic agents | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF N.Y. (US) | 1991-04-23 | — | — | US | disclosed |
| US-4927966-A | ANTITUMOR | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1990-05-22 | — | — | US | disclosed |