Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 5/20 | 0.44 |
| ▸ | ANPEP | P15144 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ACP3 | P15309 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7114956 | 0.82 | LAP3 (0.44) | LAP3ANPEPACP3ALDH1A1MAPT | |
| SCHEMBL9814756 | 0.76 | ANPEP (0.33) | LAP3ANPEP | |
| SCHEMBL22321963 | 0.72 | ACACB (0.35) | LAP3ANPEPMEN1KMT2AALDH1A1 | |
| SCHEMBL9814698 | 0.72 | MMP1 (0.30) | — | |
| SCHEMBL6553506 | 0.70 | LAP3 (0.47) | LAP3ANPEPMEN1KMT2AACP3 | |
| SCHEMBL9814714 | 0.70 | — | — | |
| SCHEMBL30064101 | 0.69 | POLB (0.44) | LAP3POLBALDH1A1MAPTCHRM1 | |
| SCHEMBL30063821 | 0.69 | PPARG (0.43) | MEN1KMT2AATM | |
| SCHEMBL6444758 | 0.69 | SLC7A5 (0.46) | — | |
| SCHEMBL27556823 | 0.69 | POLB (0.47) | ANPEPMMP8MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445201-A1 | NUCLEOSIDE ANALOGUES | MEDICAL RESEARCH COUNCIL (GB) | 1991-09-11 | — | — | EP | claimed |
| WO-1990005736-A2 | NUCLEOSIDE ANALOGUES | MEDICAL RESEARCH COUNCIL (GB) | 1990-05-31 | — | — | WO | claimed |
| EP-0445201-A1 | NUCLEOSIDE ANALOGUES | MEDICAL RESEARCH COUNCIL (GB) | 1991-09-11 | — | — | EP | disclosed |
| WO-1990005736-A2 | NUCLEOSIDE ANALOGUES | MEDICAL RESEARCH COUNCIL (GB) | 1990-05-31 | — | — | WO | disclosed |