Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31525343 | 0.83 | MGAM (0.49) | MGAMKDM4EALOX15TDP1TSHR | |
| SCHEMBL8852131 | 0.80 | MGAM (0.49) | MGAMKDM4EALOX15TDP1TSHR | |
| SCHEMBL7629466 | 0.80 | MGAM (0.56) | MGAMKDM4EALOX15TDP1TSHR | |
| SCHEMBL30744791 | 0.79 | ALOX15 (0.61) | MGAMKDM4EALOX15ALDH1A1HPGD | |
| SCHEMBL2806839 | 0.78 | MGAM (0.58) | MGAMKDM4EALOX15TDP1TSHR | |
| SCHEMBL5181112 | 0.78 | MGAM (0.58) | MGAMKDM4EALOX15TDP1TSHR | |
| SCHEMBL6197830 | 0.76 | MGAM (0.56) | MGAMKDM4EALOX15TDP1TSHR | |
| SCHEMBL18365930 | 0.76 | MGAM (0.56) | MGAMKDM4EALOX15TDP1TSHR | |
| SCHEMBL2909537 | 0.76 | MGAM (0.56) | MGAMKDM4EALOX15TDP1TSHR | |
| SCHEMBL6193849 | 0.76 | MGAM (0.56) | MGAMKDM4EALOX15TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247277-B1 | PROCESS FOR THE PREPARATION OF 5-ALKYLQUINOLINIC ACIDS AND MEANS FOR CARRYING OUT THIS PROCESS | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1991-09-11 | — | — | EP | disclosed |
| EP-0247277-A2 | Process for the preparation of 5-alkylquinolinic acids and means for carrying out this process | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1987-12-02 | — | — | EP | disclosed |