Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16328992 | 0.85 | CYP1A2 (0.47) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL901166 | 0.84 | KMT2A (0.50) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL2939781 | 0.81 | KMT2A (0.47) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL2939780 | 0.81 | KMT2A (0.47) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL10945011 | 0.80 | KMT2A (0.44) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL278717 | 0.80 | ALDH1A1 (0.44) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL20827637 | 0.80 | ALDH1A1 (0.44) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL12627456 | 0.80 | ALDH1A1 (0.45) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL18526169 | 0.79 | PPARG (0.49) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL10434347 | 0.79 | CYP1A2 (0.41) | ALDH1A1HPGDHSD17B10CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447949-A1 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-25 | — | — | EP | claimed |
| EP-0381026-A2 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1990-08-08 | — | — | EP | claimed |
| EP-2004847-B1 | OLIGONUCLEOTIDES COMPRISING SIGNALLING PAIRS AND HYDROPHOBIC NUCLEOTIDES, STEMLESS BEACONS, FOR DETECTION OF NUCLEIC ACIDS, METHYLATION STATUS AND MUTANTS OF NUCLEIC ACIDS | PENTABASE APS (DK) | 2017-05-03 | — | — | EP | disclosed |
| US-20130171027-A1 | OXYGEN SENSORS BASED ON HARD-SOFT ACID-BASE RELATIONSHIPS | HONEYWELL INTERNATIONAL INC. (US) | 2013-07-04 | — | — | US | disclosed |
| US-8211881-B2 | For detecting and measuring effects on biological membranes; cyclodextrins | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-07-03 | — | — | US | disclosed |
| US-20080187947-A1 | Cholesterol-Mimetic Pyrene Probes | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2008-08-07 | — | — | US | disclosed |
| US-7405262-B2 | Preparation of functionalized anionic polymerization initiators | BRIDGESTONE CORPORATION (JP) | 2008-07-29 | — | — | US | disclosed |
| US-7405262-B2 | Preparation of functionalized anionic polymerization initiators | BRIDGESTONE CORPORATION (JP) | 2008-07-29 | — | — | US | disclosed |
| EP-0447949-A1 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-25 | — | — | EP | disclosed |
| EP-0381026-A2 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1990-08-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080187947-A1 | Cholesterol-Mimetic Pyrene Probes | CYP46A1, CETP, CYP27A1 | ALDH1A1 4328/4885HPGD 712/4885HSD17B10 412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.