Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.63 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.63 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 8/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | STAT3 | P40763 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806842 | 1.00 | CASP3 (0.63) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL10685389 | 1.00 | CASP3 (0.63) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL9806787 | 1.00 | CASP3 (0.63) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL9806791 | 1.00 | CASP3 (0.63) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL16440913 | 0.99 | CASP3 (0.64) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL8653007 | 0.93 | CASP3 (0.54) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL9806864 | 0.90 | RAB9A (0.57) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL9806789 | 0.90 | RAB9A (0.57) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL9806771 | 0.90 | RAB9A (0.57) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL9806813 | 0.90 | RAB9A (0.63) | CASP3SENP8SENP7SENP6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233706-B1 | HALOGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM | Chisso Corporation (JP) | 1991-09-11 | — | — | EP | disclosed |
| US-4865763-A | LOW TEMPERATURE STABILITY | CHISSO CORPORATION (JP) | 1989-09-12 | — | — | US | disclosed |
| US-4765924-A | SMECTIC PHASE FORMING INHIBITION | CHISSO CORPORATION (JP) | 1988-08-23 | — | — | US | disclosed |
| EP-0233706-A2 | Halogen-containing heterocyclic compounds and liquid crystal compositions containing them | Chisso Corporation (JP) | 1987-08-26 | — | — | EP | disclosed |