Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL9815325

CCOC.CCOCC.OCCOCCO

nearest known ligand 0.68

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.68
TSHR P16473 3/20 0.56
MAPK1 P28482 2/20 0.56
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
THRB P10828 1/20 0.46
HTT P42858 1/20 0.46
MAPT P10636 1/20 0.46
USP2 O75604 1/20 0.31
LMNA P02545 1/20 0.31
CYP3A4 P08684 1/20 0.31
CASP1 P29466 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SLCO1B3 Q9NPD5 1/20 0.31
SLCO1B1 Q9Y6L6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Di(Hydroxyethyl)Ether SCHEMBL3457513 1.00 ALDH1A1 (0.68) ALDH1A1TSHRMAPK1MEN1KMT2A
Triethylene Glycol SCHEMBL21811316 0.95 ALDH1A1 (0.62) ALDH1A1TSHRMAPK1MEN1KMT2A
Di(Hydroxyethyl)Ether SCHEMBL141391 0.94 ALDH1A1 (0.67) ALDH1A1TSHRMAPK1MEN1KMT2A
Di(Hydroxyethyl)Ether SCHEMBL9045837 0.92 ALDH1A1 (0.65) ALDH1A1TSHRMAPK1MEN1KMT2A
Diethylene Glycol Monoethyl Ether SCHEMBL337049 0.92 ALDH1A1 (0.74) ALDH1A1TSHRMAPK1MEN1KMT2A
Di(Hydroxyethyl)Ether SCHEMBL29129030 0.92 ALDH1A1 (0.74) ALDH1A1TSHRMAPK1MEN1KMT2A
Di(Hydroxyethyl)Ether SCHEMBL4138266 0.92 ALDH1A1 (0.72) ALDH1A1TSHRMAPK1MEN1KMT2A
Triethylene Glycol SCHEMBL272568 0.92 MEN1 (0.65) ALDH1A1TSHRMAPK1MEN1KMT2A
Di(Hydroxyethyl)Ether SCHEMBL6329214 0.92 ALDH1A1 (0.72) ALDH1A1TSHRMAPK1MEN1KMT2A
Pentaethylene Glycol SCHEMBL11969734 0.92 MEN1 (0.65) ALDH1A1TSHRMAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0238167-B1 DYE-CONDITIONER COMPOSITION AND METHOD HELENE CURTIS, INC. (US) 1991-10-16 EP disclosed
US-4764174-A Nitrophenylenediamine dye composition having improved deposition on human hair and wool HELENE CURTIS, INC. (US) 1988-08-16 US disclosed
EP-0238167-A1 Dye-conditioner composition and method HELENE CURTIS, INC. (US) 1987-09-23 EP disclosed
US-4678475-A REDUCTION OF YELLOWING OF HAIR OR WOOL HELENE CURTIS, INC. (US) 1987-07-07 US disclosed