Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 8/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9815374 | 0.99 | CASR (0.50) | CASRABCB1ATMMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10489798 | 0.81 | ABCB1 (0.38) | ABCB1ATM | |
| Alprafenone SCHEMBL1345342 | 0.76 | ADRB2 (0.54) | CASRATMMEN1KMT2ASLC6A4 | |
| Alprafenone SCHEMBL1231193 | 0.76 | ADRB2 (0.53) | CASRMEN1KMT2ASLC6A4SLC6A3 | |
| Diprafenone SCHEMBL563653 | 0.72 | MEN1 (0.80) | ABCB1MEN1KMT2ASLC6A4SLC6A3 | |
| SCHEMBL9815362 | 0.72 | MEN1 (0.53) | CASRABCB1MEN1KMT2AADRB2 | |
| Diprafenone SCHEMBL8862790 | 0.71 | MEN1 (0.82) | ABCB1MEN1KMT2ASLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL9815365 | 0.71 | MEN1 (0.55) | CASRABCB1MEN1KMT2AADRB2 | |
| Hydrochloric Acid SCHEMBL5517365 | 0.70 | CASR (0.82) | CASRKMT2ASLC6A4SLC6A3KCNH2 | |
| SCHEMBL14383077 | 0.70 | CASR (0.78) | CASRSLC6A4SLC6A3KCNH2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297435-B1 | AMINOPROPANOL DERIVATIVES OF 3-(3'-HYDROXYPHENYL)-1-PROPANONE, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | Helopharm W. Petrik GmbH & Co.KG. (DE) | 1991-10-16 | — | — | EP | claimed |
| EP-0219130-B1 | HEAT AND PRESSURE SENSITIVE RECORDING MATERIAL | Naigai Carbon Ink Co., Ltd. (JP) | 1991-09-18 | — | — | EP | claimed |