Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9815501 | 0.88 | MAOA (0.59) | F10 | |
| SCHEMBL9823175 | 0.87 | F10 (0.62) | F10F2 | |
| SCHEMBL5764261 | 0.87 | F10 (0.54) | F10F2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9815558 | 0.84 | F10 (0.51) | F10F2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4881025 | 0.83 | F10 (0.50) | F10F2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5216980 | 0.83 | MAOA (0.60) | F10F2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9815544 | 0.83 | F10 (0.52) | F10F2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9815493 | 0.82 | F10 (0.49) | F10F2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9815509 | 0.82 | F10 (0.49) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14838774 | 0.81 | F10 (0.73) | F10F2CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127902-B1 | AMINOMETHYL OXOOXAZOLIDINYL BENZENE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-16 | — | — | EP | disclosed |
| US-4705799-A | Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-10 | — | — | US | disclosed |
| EP-0127902-A2 | Aminomethyl oxooxazolidinyl benzene derivatives useful as antibacterial agents | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-12-12 | — | — | EP | disclosed |