SCHEMBL9823175

SCHEMBL9823175

O=C(O)NCC1CN(c2ccc(Cl)cc2)C(=O)O1

nearest known ligand 0.62

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 17/20 0.62
GRM2 Q14416 2/20 0.55
F2 P00734 1/20 0.54
ABCB11 O95342 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9815523 0.87 F10 (0.54) F10F2
SCHEMBL5764261 0.87 F10 (0.54) F10F2
SCHEMBL9815558 0.84 F10 (0.51) F10F2
SCHEMBL4881025 0.83 F10 (0.50) F10F2ABCB11
SCHEMBL9815544 0.83 F10 (0.52) F10F2
SCHEMBL5216980 0.83 MAOA (0.60) F10F2
SCHEMBL14161964 0.82 ABCB11 (0.58) F10GRM2ABCB11
SCHEMBL9815493 0.82 F10 (0.49) F10F2
SCHEMBL9815509 0.82 F10 (0.49) F10
SCHEMBL16467069 0.81 F10 (0.73) F10F2ABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0184170-B1 AMINOMETHYL OXOOXAZOLIDINYL BENZENE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-16 EP disclosed
EP-0184170-A2 Aminomethyl oxooxazolidinyl benzene derivatives useful as antibacterial agents E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-06-11 EP disclosed