Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | CALML3 | P27482 | 6/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA4 | P22748 | 3/20 | 0.48 |
| ▸ | CA6 | P23280 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4399815 | 1.00 | MAOA (0.53) | MAOAMAOBCALML3CA12CA1 | |
| SCHEMBL9815526 | 0.86 | MAOA (0.56) | MAOAMAOBCALML3GRM2 | |
| SCHEMBL10878982 | 0.86 | MAOA (0.56) | MAOAMAOBCALML3GRM2 | |
| SCHEMBL22245070 | 0.85 | CALML3 (0.71) | MAOAMAOBCALML3 | |
| SCHEMBL29432582 | 0.85 | CALML3 (0.71) | MAOAMAOBCALML3 | |
| SCHEMBL11063292 | 0.83 | GRM2 (0.50) | MAOACA12CA1CA2CA4 | |
| SCHEMBL14183666 | 0.83 | MAOA (0.53) | MAOAMAOBCALML3GRM2F10 | |
| SCHEMBL11062676 | 0.83 | MAOA (0.50) | MAOAMAOBCALML3GRM2F10 | |
| SCHEMBL22245004 | 0.83 | CALML3 (0.55) | MAOAMAOBCALML3GRM2 | |
| SCHEMBL10923841 | 0.83 | MAOA (0.53) | MAOAMAOBCALML3GRM2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0081200-B1 | P-OXOOXAZOLIDINYLBENZENE SULFONAMIDES AS ANTIBACTERIAL AGENTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-10-08 | — | — | EP | claimed |
| US-4461773-A | P-Oxooxazolidinylbenzene compounds as antibacterial agents | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1984-07-24 | — | — | US | claimed |
| EP-0081200-A1 | p-Oxooxazolidinylbenzene sulfonamides as antibacterial agents | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-06-15 | — | — | EP | claimed |
| EP-0127902-B1 | AMINOMETHYL OXOOXAZOLIDINYL BENZENE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-16 | — | — | EP | disclosed |
| US-4705799-A | Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-10 | — | — | US | disclosed |
| EP-0081200-B1 | P-OXOOXAZOLIDINYLBENZENE SULFONAMIDES AS ANTIBACTERIAL AGENTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-10-08 | — | — | EP | disclosed |
| EP-0127902-A2 | Aminomethyl oxooxazolidinyl benzene derivatives useful as antibacterial agents | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-12-12 | — | — | EP | disclosed |
| US-4461773-A | P-Oxooxazolidinylbenzene compounds as antibacterial agents | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1984-07-24 | — | — | US | disclosed |
| US-4461773-A | P-Oxooxazolidinylbenzene compounds as antibacterial agents | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1984-07-24 | — | — | US | disclosed |
| EP-0081200-A1 | p-Oxooxazolidinylbenzene sulfonamides as antibacterial agents | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-06-15 | — | — | EP | disclosed |
| EP-0081200-A1 | p-Oxooxazolidinylbenzene sulfonamides as antibacterial agents | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-06-15 | — | — | EP | disclosed |