Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | GRM2 | Q14416 | 8/20 | 0.50 |
| ▸ | CALML3 | P27482 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10878982 | 1.00 | MAOA (0.56) | MAOAMAOBGRM2CALML3 | |
| SCHEMBL22245004 | 0.96 | CALML3 (0.55) | MAOAMAOBGRM2CALML3 | |
| SCHEMBL14274376 | 0.87 | MAOB (0.52) | MAOAMAOBGRM2CALML3 | |
| SCHEMBL9815590 | 0.86 | F10 (0.57) | GRM2 | |
| SCHEMBL9815504 | 0.86 | GRM2 (0.50) | GRM2 | |
| SCHEMBL9815528 | 0.86 | MAOA (0.53) | MAOAMAOBGRM2CALML3 | |
| SCHEMBL9815487 | 0.86 | GRM2 (0.50) | MAOBGRM2 | |
| SCHEMBL11594531 | 0.86 | GRM2 (0.50) | MAOBGRM2 | |
| SCHEMBL9815496 | 0.86 | GRM2 (0.50) | GRM2 | |
| SCHEMBL4399815 | 0.86 | MAOA (0.53) | MAOAMAOBGRM2CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127902-B1 | AMINOMETHYL OXOOXAZOLIDINYL BENZENE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-16 | — | — | EP | disclosed |
| US-4705799-A | Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-10 | — | — | US | disclosed |
| EP-0050827-B1 | 3-(P-ALKYLSULFONYLPHENYL)-AND 3-(P-ALKYLSULFINYLPHENYL)OXAZOLIDINONE DERIVATIVES AS ANTI-BACTERIAL AGENTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-04-30 | — | — | EP | disclosed |
| EP-0127902-A2 | Aminomethyl oxooxazolidinyl benzene derivatives useful as antibacterial agents | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-12-12 | — | — | EP | disclosed |
| US-4340606-A | 3-(p-Alkylsulfonylphenyl)oxazolidinone derivatives as antibacterial agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-07-20 | — | — | US | disclosed |
| EP-0050827-A1 | 3-(p-Alkylsulfonylphenyl)-and 3-(p-alkylsulfinylphenyl)oxazolidinone derivatives as anti-bacterial agents | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-05-05 | — | — | EP | disclosed |