SCHEMBL981554

SCHEMBL981554

CCCc1cccc(=O)o1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.41
CTRC Q99895 2/20 0.39
CA12 O43570 1/20 0.37
MAPT P10636 5/20 0.36
RAB9A P51151 2/20 0.36
POLB P06746 1/20 0.36
CASP6 P55212 1/20 0.36
ELAVL1 Q15717 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.36
ELANE P08246 3/20 0.36
ALDH1A1 P00352 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TSHR P16473 1/20 0.34
HSD17B3 P37058 1/20 0.34
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
ALOX15 P16050 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MAPKAPK2 P49137 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11322723 0.88 CTRC (0.49) CYP2A6CTRCCA12MAPTALDH1A1
SCHEMBL968257 0.86 MAPT (0.47) CYP2A6CTRCMAPTELANESMN1; SMN2
SCHEMBL5311171 0.86 MAPT (0.47) CYP2A6CTRCMAPTELANESMN1; SMN2
SCHEMBL11774947 0.84 MAPT (0.50) CTRCMAPTELANESMN1; SMN2ALOX15
SCHEMBL979708 0.82
SCHEMBL9027254 0.78 PDE4D (0.40) MAPTRAB9APOLBCASP6ELAVL1
SCHEMBL21024529 0.75 EPHX2 (0.50) MAPTELANEALDH1A1MEN1KMT2A
SCHEMBL9026440 0.75 CA12 (0.50) CTRCCA12ALDH1A1TSHRHSD17B3
Viridepyronone SCHEMBL18270619 0.75 ALDH1A1 (0.40) CTRCCA12MAPTPOLBALDH1A1
SCHEMBL19679869 0.75 MAPT (0.35) CYP2A6MAPTRAB9APOLBCASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 CN claimed
CN-107426992-B Composition comprising a pesticide and isononanoic acid N, N-dimethylamide 巴斯夫欧洲公司 2021-10-15 CN disclosed
EP-2861208-A1 PREVENTION OF FIBROBLAST COLLAPSE Biocogent, LLC (US) 2015-04-22 EP disclosed
US-20150104399-A1 PREVENTION OF FIBROBLAST COLLAPSE BIOCOGENT, LLC (US) 2015-04-16 US disclosed
WO-2013173353-A1 PREVENTION OF FIBROBLAST COLLAPSE BIOCOGENT, LLC (US) 2013-11-21 WO disclosed
US-20110014504-A1 LITHIUM SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2011-01-20 US disclosed
US-20080311478-A1 Lithium Secondary Battery MITSUBISHI CHEMICAL CORPORATION (JP) 2008-12-18 US disclosed
EP-1892789-A1 LITHIUM SECONDARY BATTERY Mitsubishi Chemical Corporation (JP) 2008-02-27 EP disclosed
US-3996170-A 6-N-Butyl alpha pyrone perfumes INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-12-07 US disclosed
US-3977419-A TOBACCO ARTICLE COMPRISING A FLAVORING COMPOSITION SELECTED FROM BUTANONE DERIVATIVES AND THE PROCESS FOR MAKING THE SAME INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-08-31 US disclosed
US-3977418-A TOBACCO ARTICLE COMPRISING THE FLAVORING COMPOSITION TRICYCLENE-9-BUTENONE AND THE PROCESS FOR MAKING THE SAME INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-08-31 US disclosed