Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096279 | 0.88 | MAPT (0.51) | MAPTNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL10788212 | 0.85 | NPC1 (0.53) | MAPTNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL9815538 | 0.83 | MAPT (0.47) | TYMSMAPTNPC1RAB9ACYP1A2 | |
| SCHEMBL914221 | 0.82 | MAPT (0.52) | MAPTNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL10936116 | 0.81 | DHFR (0.42) | MAPTNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL8213468 | 0.81 | MAPT (0.46) | MAPTNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL3252488 | 0.81 | MAPT (0.54) | MAPTNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL7098554 | 0.81 | MAPT (0.50) | MAPTNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL28728255 | 0.81 | MAPT (0.43) | MAPTNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL29264291 | 0.80 | MAPT (0.47) | MAPTNPC1RAB9ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277915-B1 | PHOTOINITIATOR MIXTURE CONTAINING A TITANOCENE AND A 3-KETOCOUMARIN | CIBA-GEIGY AG (CH) | 1991-09-04 | — | — | EP | disclosed |
| EP-0304403-A2 | Plastic composition containing superconductors | CIBA-GEIGY AG (CH) | 1989-02-22 | — | — | EP | disclosed |