Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 11/20 | 0.44 |
| ▸ | MAOB | P27338 | 11/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9815568 | 0.83 | TYMS (0.47) | MAPTALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL9455912 | 0.82 | MAPT (0.49) | MAPTALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL13226079 | 0.82 | MAPT (0.60) | MAPTALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL9128843 | 0.77 | MAPT (0.55) | MAPTALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL10669824 | 0.77 | MAPT (0.60) | MAPTALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL10498726 | 0.76 | MAOA (0.49) | MAPTALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL11167133 | 0.74 | MAPT (0.53) | MAPTALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL51833 | 0.73 | GABRP (0.50) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL29501112 | 0.73 | GABRP (0.50) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL10788212 | 0.72 | NPC1 (0.53) | MAPTALDH1A1NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277915-B1 | PHOTOINITIATOR MIXTURE CONTAINING A TITANOCENE AND A 3-KETOCOUMARIN | CIBA-GEIGY AG (CH) | 1991-09-04 | — | — | EP | disclosed |