Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9815602 | 0.88 | MEN1 (0.46) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9815632 | 0.84 | CYP3A4 (0.54) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9815610 | 0.81 | MEN1 (0.44) | MEN1KMT2AMAPTLMNAGAA | |
| SCHEMBL9815622 | 0.73 | CYP3A4 (0.48) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11758665 | 0.72 | NPC1 (0.52) | MEN1KMT2ACYP1A2MAPTKDM4E | |
| SCHEMBL9813043 | 0.71 | GAA (0.52) | MEN1KMT2ACYP3A4CYP2D6MAPT | |
| SCHEMBL9815604 | 0.70 | MEN1 (0.45) | MEN1KMT2AMAPK1KDM4EALDH1A1 | |
| SCHEMBL3103923 | 0.70 | GAA (0.53) | MEN1KMT2AMAPTLMNAGAA | |
| SCHEMBL11762690 | 0.67 | KMT2A (0.56) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL11759526 | 0.67 | ALDH1A1 (0.49) | MEN1KMT2AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266549-B1 | CINNAMYL AMINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-06-19 | — | — | EP | disclosed |