Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | EP300 | Q09472 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9815610 | 0.87 | MEN1 (0.44) | MEN1KMT2AHTTTSHRKDM4E | |
| SCHEMBL9815602 | 0.79 | MEN1 (0.46) | MEN1KMT2AHTTTSHRKDM4E | |
| SCHEMBL9815634 | 0.78 | CYP3A4 (0.46) | MEN1KMT2AHTTTSHRALDH1A1 | |
| SCHEMBL9815609 | 0.70 | MEN1 (0.45) | MEN1KMT2AHTTKDM4EL3MBTL1 | |
| SCHEMBL7413309 | 0.70 | GAA (0.55) | HTTKDM4EALDH1A1 | |
| SCHEMBL16884088 | 0.69 | HTT (0.76) | MEN1KMT2AHTTTSHRKDM4E | |
| SCHEMBL10899727 | 0.69 | GAA (0.71) | HTTKDM4EALDH1A1MAPK1 | |
| SCHEMBL9813087 | 0.66 | GAA (0.50) | HTTKDM4EALDH1A1MAPK1 | |
| SCHEMBL4698558 | 0.65 | HTT (0.65) | MEN1KMT2AHTTTSHRALDH1A1 | |
| SCHEMBL4145433 | 0.64 | HTT (0.66) | HTTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266549-B1 | CINNAMYL AMINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-06-19 | — | — | EP | disclosed |