Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 2/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9425269 | 0.92 | GRM4 (0.53) | GRM4ABCB1 | |
| SCHEMBL9815854 | 0.89 | ABCB1 (0.58) | ABCB1 | |
| SCHEMBL9511093 | 0.82 | AGTR1 (0.55) | — | |
| SCHEMBL9815793 | 0.81 | ABCB1 (0.62) | ABCB1 | |
| SCHEMBL9425386 | 0.81 | ABCB1 (0.62) | ABCB1 | |
| SCHEMBL9815835 | 0.80 | ABCB1 (0.52) | ABCB1 | |
| SCHEMBL8173935 | 0.79 | POLB (0.55) | — | |
| SCHEMBL9509589 | 0.79 | MEN1 (0.57) | GRM4ABCB1 | |
| SCHEMBL8773648 | 0.78 | ABCB1 (0.62) | ABCB1 | |
| SCHEMBL10718766 | 0.77 | ABCB1 (0.63) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253468-B1 | SIX-MEMBERED HETEROCYCLIC DERIVATIVES OF N'SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-11-06 | — | — | EP | disclosed |