Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.76 |
| ▸ | MAPT | P10636 | 5/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9815962 | 0.86 | ABCB1 (0.77) | ABCB1 | |
| SCHEMBL8613867 | 0.84 | MAPT (0.82) | HTR7MAPTALOX15L3MBTL1MAPK1 | |
| SCHEMBL9815960 | 0.84 | KCNH2 (0.69) | HTR7MAPTALOX15MAPK1ALDH1A1 | |
| SCHEMBL12577217 | 0.83 | MAPT (1.00) | HTR7MAPTALOX15L3MBTL1MAPK1 | |
| SCHEMBL12575381 | 0.83 | MAPT (1.00) | HTR7MAPTALOX15L3MBTL1MAPK1 | |
| SCHEMBL12577234 | 0.83 | MAPT (0.81) | HTR7MAPTALOX15L3MBTL1MAPK1 | |
| SCHEMBL12259197 | 0.82 | MAPT (0.76) | HTR7MAPTALOX15L3MBTL1MAPK1 | |
| SCHEMBL19852033 | 0.82 | ABCB1 (0.80) | HTR7MAPTALOX15L3MBTL1MAPK1 | |
| SCHEMBL25097473 | 0.82 | MAPT (0.79) | HTR7MAPTALOX15L3MBTL1MAPK1 | |
| SCHEMBL8009539 | 0.82 | MAPT (0.79) | HTR7MAPTALOX15L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0167121-B1 | SUBSTITUTED PHENYLPIPERAZINYL PROPANOLS, PROCESS FOR THEIR PREPARATION, THEIR USE, AND COMPOSITIONS CONTAINING THESE COMPOUNDS | Beiersdorf Aktiengesellschaft (DE) | 1991-10-23 | — | — | EP | disclosed |
| US-4631281-A | ANTICOAGULANTS, ASTHMA, HYPOTENSIVE AGENTS, BRONCHOPILATORS, INOTROPIC AGENTS | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1986-12-23 | — | — | US | disclosed |
| EP-0167121-A2 | Substituted phenylpiperazinyl propanols, process for their preparation, their use, and compositions containing these compounds | Beiersdorf Aktiengesellschaft (DE) | 1986-01-08 | — | — | EP | disclosed |