Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.69 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 7/20 | 0.63 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816000 | 0.89 | MAPT (0.64) | KCNH2CACNA1GMAPTALDH1A1LMNA | |
| SCHEMBL9815962 | 0.88 | ABCB1 (0.77) | ABCB1 | |
| SCHEMBL17313697 | 0.86 | KCNH2 (0.78) | KCNH2CACNA1GMAPTALDH1A1LMNA | |
| SCHEMBL11817687 | 0.85 | CACNA1G (0.80) | KCNH2CACNA1GMAPTALDH1A1LMNA | |
| SCHEMBL9815965 | 0.84 | HTR7 (0.76) | MAPTALDH1A1LMNAMAPK1MEN1 | |
| Hydrochloric Acid SCHEMBL11813716 | 0.84 | CACNA1G (0.79) | KCNH2CACNA1GMAPTALDH1A1LMNA | |
| SCHEMBL17313690 | 0.81 | MAPT (0.74) | KCNH2CACNA1GMAPTALDH1A1LMNA | |
| SCHEMBL9815963 | 0.81 | ABCB1 (0.67) | MEN1KMT2AABCB1 | |
| SCHEMBL9815982 | 0.81 | KCNH2 (0.61) | KCNH2CACNA1GMAPTALDH1A1LMNA | |
| Enciprazine SCHEMBL584730 | 0.80 | MAPT (0.74) | KCNH2CACNA1GMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0167121-B1 | SUBSTITUTED PHENYLPIPERAZINYL PROPANOLS, PROCESS FOR THEIR PREPARATION, THEIR USE, AND COMPOSITIONS CONTAINING THESE COMPOUNDS | Beiersdorf Aktiengesellschaft (DE) | 1991-10-23 | — | — | EP | disclosed |
| US-4631281-A | ANTICOAGULANTS, ASTHMA, HYPOTENSIVE AGENTS, BRONCHOPILATORS, INOTROPIC AGENTS | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1986-12-23 | — | — | US | disclosed |