Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.51 |
| ▸ | GRM8 | O00222 | 4/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29355173 | 0.83 | LTA4H (0.54) | LTA4HGRM8GRM4 | |
| SCHEMBL14586345 | 0.83 | LTA4H (0.54) | LTA4HGRM8GRM4 | |
| SCHEMBL1870730 | 0.83 | LTA4H (0.54) | LTA4HGRM8GRM4 | |
| Ammonia Solution, Strong SCHEMBL9816149 | 0.82 | LTA4H (0.53) | LTA4HGRM8GRM4 | |
| Ammonia Solution, Strong SCHEMBL29399251 | 0.82 | LTA4H (0.53) | LTA4HGRM8GRM4 | |
| SCHEMBL9816016 | 0.82 | LTA4H (0.53) | LTA4HGRM8GRM4 | |
| Ammonia Solution, Strong SCHEMBL29370733 | 0.82 | LTA4H (0.53) | LTA4HGRM8GRM4 | |
| SCHEMBL9816111 | 0.80 | LTA4H (0.51) | LTA4HGRM8GRM4 | |
| SCHEMBL11097431 | 0.80 | LTA4H (0.51) | LTA4HGRM8GRM4 | |
| SCHEMBL9816133 | 0.80 | LTA4H (0.51) | LTA4HGRM8GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297607-B1 | GAMMA-L-GLUTAMYL-4-NITROANILIDE DERIVATIVES AND PROCESS FOR DETERMINING GAMMA-GTP ACTIVITY USING THE SAME | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-28 | — | — | EP | claimed |
| US-4851572-A | DIAGNOSIS OF LIVER AND BILE DUCT DISORDERS, ALCOHOLISM | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1989-07-25 | — | — | US | claimed |
| EP-0297607-A1 | Gamma-L-glutamyl-4-nitroanilide derivatives and process for determining gamma-GTP activity using the same | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1989-01-04 | — | — | EP | claimed |
| EP-0297607-B1 | GAMMA-L-GLUTAMYL-4-NITROANILIDE DERIVATIVES AND PROCESS FOR DETERMINING GAMMA-GTP ACTIVITY USING THE SAME | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4851572-A | DIAGNOSIS OF LIVER AND BILE DUCT DISORDERS, ALCOHOLISM | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0297607-A1 | Gamma-L-glutamyl-4-nitroanilide derivatives and process for determining gamma-GTP activity using the same | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1989-01-04 | — | — | EP | disclosed |