Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816042 | 0.78 | ALDH1A1 (0.34) | ALDH1A1MAPTNPSR1 | |
| SCHEMBL3258454 | 0.74 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2DPP4MAPTPOLB | |
| SCHEMBL11616346 | 0.72 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2DPP4MAPTPOLB | |
| SCHEMBL173228 | 0.72 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2DPP4MAPTPOLB | |
| SCHEMBL13786 | 0.71 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2DPP4MAPTPOLB | |
| SCHEMBL569156 | 0.71 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2DPP4MAPTPOLB | |
| SCHEMBL88005 | 0.69 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2DPP4MAPTPOLB | |
| SCHEMBL88004 | 0.69 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2DPP4MAPTPOLB | |
| SCHEMBL8474273 | 0.68 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2DPP4MAPTPOLB | |
| SCHEMBL3840012 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0404250-A3 | PREPARATION OF N,N-DIALKYLCARBAMOYLMETHYLPHOSPHINE OXIDE | AKZO N.V. (NL) | 1991-10-02 | — | — | EP | disclosed |
| EP-0404250-A2 | Preparation of N,N-dialkylcarbamoylmethylphosphine oxide | AKZO N.V. (NL) | 1990-12-27 | — | — | EP | disclosed |