SCHEMBL9816218

SCHEMBL9816218

C=CC[Si](c1ccccc1)C(N)C=C

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9816210 0.74 DPP4 (0.33)
SCHEMBL1936275 0.69 ALDH1A1 (0.36) CYP2C19
SCHEMBL5881375 0.69 ALDH1A1 (0.36) CYP2C19
Fluoride SCHEMBL27912993 0.67 ALDH1A1 (0.35) CYP2C19
SCHEMBL8992320 0.66 ALDH1A1 (0.33) CYP2C19
SCHEMBL7193217 0.66 ALDH1A1 (0.33) CYP2C19
SCHEMBL4456337 0.58 DPP4 (0.39) CYP2C19
SCHEMBL24931234 0.57 EPHX1 (0.56)
SCHEMBL433275 0.57 EPHX1 (0.56)
SCHEMBL7406881 0.57 CYP2C19 (0.57) CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4994591-A Antitumor, anticarcinogenic agents THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NY (US) 1991-02-19 US disclosed