SCHEMBL9816245

SCHEMBL9816245

Brc1cc(Br)c(C(Br)C(Br)COCC(Br)C(Br)c2c(Br)cc(Br)cc2Br)c(Br)c1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10824436 0.72 TSHR (0.37) CYP3A4TSHRTDP1
SCHEMBL9816242 0.69 CYP3A4 (0.30) CYP3A4TSHRTDP1
SCHEMBL2883398 0.65 ALDH1A1 (0.44) ALDH1A1CYP3A4TSHRTDP1
SCHEMBL10192340 0.65 ALDH1A1 (0.44) ALDH1A1CYP3A4TSHRTDP1
SCHEMBL4091711 0.63 TDP1 (0.45) ALDH1A1CYP3A4TSHRTDP1
SCHEMBL11351224 0.63
SCHEMBL10832001 0.62 CYP3A4 (0.39) CYP3A4TSHRTDP1
SCHEMBL7786052 0.62 CYP3A4 (0.40) CYP3A4TSHRTDP1
SCHEMBL5440832 0.61 ALDH1A1 (0.67) ALDH1A1CYP3A4TSHRTDP1
SCHEMBL9066390 0.61 CYP3A4 (0.33) ALDH1A1CYP3A4TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3140363-A None JP disclosed
JP-H03140363-A FLAME-RETARDANT POLYURETHANE FOAM MANATSUKU KK 1991-06-14 JP disclosed
US-4171295-A Aqueous emulsions of polyolefins/bitumen plastic or plastic-elastic materials and process for the production thereof CHEMISCHE WERKE HUELS AKTIENGESELLSCHAFT (DE) 1979-10-16 US disclosed
US-3962164-A A DIPHENYL, ANTIMONY TRIOXIDE OR OXYCHLORIDE, ORGANO-CHLORO, AROMATIC BROMINE CHEMISCHE FABRIK KALK GMBH (DT) 1976-06-08 US disclosed