Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786052 | 0.77 | CYP3A4 (0.40) | TSHRCYP3A4TDP1GABRA1GABRB1 | |
| SCHEMBL7152624 | 0.76 | TDP1 (0.39) | TSHRCYP3A4TDP1GABRA1GABRB1 | |
| SCHEMBL9816245 | 0.72 | ALDH1A1 (0.32) | TSHRCYP3A4TDP1 | |
| SCHEMBL29123796 | 0.71 | CYP3A4 (0.34) | TSHRCYP3A4TDP1GABRA1GABRB1 | |
| SCHEMBL5478851 | 0.65 | TSHR (0.58) | TSHRCYP3A4TDP1 | |
| SCHEMBL10824435 | 0.65 | CYP3A4 (0.37) | TSHRCYP3A4TDP1GABRA1GABRB1 | |
| SCHEMBL4091711 | 0.65 | TDP1 (0.45) | TSHRCYP3A4TDP1GABRA1GABRB1 | |
| SCHEMBL9319827 | 0.63 | TSHR (0.48) | TSHRCYP3A4TDP1 | |
| SCHEMBL680993 | 0.63 | TSHR (0.48) | TSHRCYP3A4TDP1 | |
| SCHEMBL10711308 | 0.61 | TSHR (0.54) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61091231-A | — | — | None | — | — | JP | disclosed |
| JP-61085444-A | — | — | None | — | — | JP | disclosed |
| JP-61085453-A | — | — | None | — | — | JP | disclosed |
| JP-S6191231-A | PRODUCTION OF FLAME RETARDANT | HITACHI CHEM CO LTD | 1986-05-09 | — | — | JP | disclosed |
| JP-S6185453-A | PRODUCTION OF FLAME-RETARDANT | HITACHI CHEM CO LTD | 1986-05-01 | — | — | JP | disclosed |
| JP-S6185444-A | PRODUCTION OF FLAME-RETARDANT PHENOLIC RESIN LAMINATE | HITACHI CHEM CO LTD | 1986-05-01 | — | — | JP | disclosed |