SCHEMBL9816286

SCHEMBL9816286

CCOc1ccc(C#Cc2ccc(OC(F)(F)F)cc2)nc1

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACACB O00763 11/20 0.52
L3MBTL1 Q9Y468 1/20 0.47
MCHR1 Q99705 2/20 0.42
CACNA2D1 P54289 1/20 0.40
NQO1 P15559 1/20 0.39
CCR6 P51684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9713293 0.89 ACACB (0.51) ACACBMCHR1
SCHEMBL9712769 0.89 ACACB (0.56) ACACBMCHR1
SCHEMBL9713556 0.88 ACACB (0.52) ACACBL3MBTL1MCHR1
SCHEMBL9713057 0.87 ACACB (0.49) ACACBL3MBTL1MCHR1
SCHEMBL9510160 0.87 L3MBTL1 (0.58) ACACBL3MBTL1CACNA2D1NQO1
SCHEMBL9713010 0.86 ACACB (0.49) ACACBL3MBTL1MCHR1
SCHEMBL9712808 0.86 ACACB (0.48) ACACBL3MBTL1MCHR1
SCHEMBL9713683 0.86 ACACB (0.48) ACACBL3MBTL1MCHR1
SCHEMBL9712970 0.86 ACACB (0.48) ACACBL3MBTL1MCHR1
SCHEMBL9713366 0.86 ACACB (0.49) ACACBMCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0306521-B1 ETHINE DERIVATIVES AS COMPOUNDS OF LIQUID CRYSTAL PHASES MERCK PATENT GmbH (DE) 1991-10-16 EP disclosed