SCHEMBL9816481

SCHEMBL9816481

Cc1ccc(S(=O)(=O)Nc2c(C(=O)O)[nH]c3ccccc23)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 16/20 0.79
KMT2A Q03164 16/20 0.79
GFER P55789 6/20 0.79
GAA P10253 15/20 0.76
ALDH1A1 P00352 6/20 0.71
HTT P42858 3/20 0.71
ATM Q13315 1/20 0.71
KDM4E B2RXH2 7/20 0.67
MAPT P10636 4/20 0.67
HSD17B10 Q99714 5/20 0.66
HPGD P15428 3/20 0.66
SMN1; SMN2 Q16637 1/20 0.60
GSK3A P49840 1/20 0.58
GSK3B P49841 1/20 0.58
CDK5 Q00535 1/20 0.58
CDK5R1 Q15078 1/20 0.58
TSHR P16473 2/20 0.56
LMNA P02545 1/20 0.56
PKM P14618 1/20 0.56
KEAP1 Q14145 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8938275 0.83 MEN1 (0.67) MEN1KMT2AGFERGAAALDH1A1
SCHEMBL8792068 0.82 MEN1 (0.74) MEN1KMT2AGFERGAAALDH1A1
SCHEMBL10772446 0.81 MEN1 (0.55) MEN1KMT2AGFERGAAALDH1A1
SCHEMBL8938474 0.77 MEN1 (0.62) MEN1KMT2AGFERGAAALDH1A1
SCHEMBL6950268 0.76 HTT (0.60) MEN1KMT2AGFERGAAALDH1A1
SCHEMBL8550589 0.75 LMNA (0.49) MEN1KMT2AGFERGAAALDH1A1
SCHEMBL5949363 0.73 KEAP1 (0.61) MEN1KMT2AALDH1A1HTTMAPT
SCHEMBL9816506 0.73 KDM4E (1.00) MEN1KMT2AGFERGAAALDH1A1
SCHEMBL28243597 0.73 KDM4E (0.65) MEN1KMT2AGFERGAAALDH1A1
SCHEMBL27785395 0.72 MEN1 (0.66) MEN1KMT2AGFERGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0234540-B1 HEAT-SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1991-10-16 EP disclosed
US-4731353-A METAL SALT OF INDOLE-2-CARBOXYLIC ACID COLOR DEVELOPER KANZAKI PAPER MANUFACTURING COMPANY, LIMITED (JP) 1988-03-15 US disclosed